# 4. Hypothesis

It is the mark of a truly intelligent person to be moved by statistics. George Bernard Shaw

What will we do with all this statistics and probability theory? The science part of data science frequently involves forming and testing hypotheses about our data and the processes that generate it.

## Statistical Hypothesis Testing

Often, as data scientists, we’ll want to test whether a certain hypothesis is likely to be true. For our purposes, hypotheses are assertions like “this coin is fair” or “data scientists prefer Python to R” or “people are more likely to navigate away from the page without ever reading the content if we pop up an irritating interstitial advertisement with a tiny, hard-to- find close button” that can be translated into statistics about data. Under various assumptions, those statistics can be thought of as observations of random variables from known distributions, which allows us to make statements about how likely those assumptions are to hold.

In the classical setup, we have a null hypothesis that represents some default position, and some alternative hypothesis that we’d like to compare it with. We use statistics to decide whether we can reject as false or not. This will probably make more sense with an example.

## Example: Flipping a Coin

Imagine we have a coin and we want to test whether it’s fair. We’ll make the assumption that the coin has some probability p of landing heads, and so our null hypothesis is that the coin is fair — that is, that . We’ll test this against the alternative hypothesis .

In particular, our test will involve flipping the coin some number n times and counting the number of heads X. Each coin flip is a Bernoulli trial, which means that X is a Binomial(n,p) random variable, which (as we saw in Chapter 6) we can approximate using the normal distribution:

def normal_approximation_to_binomial(n, p):

"""finds mu and sigma corresponding to a Binomial(n, p)"""

mu = p * n

sigma = math.sqrt(p * (1 - p) * n)

return mu, sigma

Whenever a random variable follows a normal distribution, we can use normal_cdf to figure out the probability that its realized value lies within (or outside) a particular interval:

# the normal cdf _is_ the probability the variable is below a threshold

normal_probability_below = normal_cdf

# it's above the threshold if it's not below the threshold

def normal_probability_above(lo, mu=0, sigma=1):

return 1 - normal_cdf(lo, mu, sigma)

# it's between if it's less than hi, but not less than lo

def normal_probability_between(lo, hi, mu=0, sigma=1):

return normal_cdf(hi, mu, sigma) - normal_cdf(lo, mu, sigma)

# it's outside if it's not between

def normal_probability_outside(lo, hi, mu=0, sigma=1):

return 1 - normal_probability_between(lo, hi, mu, sigma)

We can also do the reverse — find either the nontail region or the (symmetric) interval around the mean that accounts for a certain level of likelihood. For example, if we want to find an interval centered at the mean and containing 60% probability, then we find the cutoffs where the upper and lower tails each contain 20% of the probability (leaving 60%):

def normal_upper_bound(probability, mu=0, sigma=1): """returns the z for which P(Z <= z) = probability""" return inverse_normal_cdf(probability, mu, sigma)

def normal_lower_bound(probability, mu=0, sigma=1): """returns the z for which P(Z >= z) = probability""" return inverse_normal_cdf(1 - probability, mu, sigma)

def normal_two_sided_bounds(probability, mu=0, sigma=1): """returns the symmetric (about the mean) bounds that contain the specified probability""" tail_probability = (1 - probability) / 2

# upper bound should have tail_probability above it

upper_bound = normal_lower_bound(tail_probability, mu, sigma)

# lower bound should have tail_probability below it

lower_bound = normal_upper_bound(tail_probability, mu, sigma)

return lower_bound, upper_bound

In particular, let’s say that we choose to flip the coin times. If our hypothesis of fairness is true, X should be distributed approximately normally with mean 50 and standard deviation 15.8:

mu_0, sigma_0 = normal_approximation_to_binomial(1000, 0.5)

We need to make a decision about significance — how willing we are to make a type 1 error (“false positive”), in which we reject even though it’s true. For reasons lost to the annals of history, this willingness is often set at 5% or 1%. Let’s choose 5%.

Consider the test that rejects if X falls outside the bounds given by:

normal_two_sided_bounds(0.95, mu_0, sigma_0) # (469, 531)

Assuming p really equals 0.5 (i.e., is true), there is just a 5% chance we observe an X that lies outside this interval, which is the exact significance we wanted. Said differently, if is true, then, approximately 19 times out of 20, this test will give the correct result.

We are also often interested in the power of a test, which is the probability of not making a type 2 error, in which we fail to reject even though it’s false. In order to measure this, we have to specify what exactly being false means. (Knowing merely that p is not 0.5 doesn’t give you a ton of information about the distribution of X.) In particular, let’s check what happens if p is really 0.55, so that the coin is slightly biased toward heads.

In that case, we can calculate the power of the test with:

# 95% bounds based on assumption p is 0.5

lo, hi = normal_two_sided_bounds(0.95, mu_0, sigma_0)

# actual mu and sigma based on p = 0.55

mu_1, sigma_1 = normal_approximation_to_binomial(1000, 0.55)

# a type 2 error means we fail to reject the null hypothesis # which will happen when X is still in our original interval

type_2_probability = normal_probability_between(lo, hi, mu_1, sigma_1) power = 1 - type_2_probability # 0.887

Imagine instead that our null hypothesis was that the coin is not biased toward heads, or that . In that case we want a one-sided test that rejects the null hypothesis when X is much larger than 50 but not when X is smaller than 50. So a 5%-significance test involves using normal_probability_below to find the cutoff below which 95% of the probability lies:

hi = normal_upper_bound(0.95, mu_0, sigma_0)

# is 526 (< 531, since we need more probability in the upper tail)

type_2_probability = normal_probability_below(hi, mu_1, sigma_1)

power = 1 - type_2_probability # 0.936

This is a more powerful test, since it no longer rejects when X is below 469 (which is very unlikely to happen if is true) and instead rejects when X is between 526 and 531 (which is somewhat likely to happen if is true). === p-values

An alternative way of thinking about the preceding test involves p-values. Instead of choosing bounds based on some probability cutoff, we compute the probability — assuming is true — that we would see a value at least as extreme as the one we actually observed.

For our two-sided test of whether the coin is fair, we compute:

def two_sided_p_value(x, mu=0, sigma=1):

if x >= mu:

# if x is greater than the mean, the tail is what's greater than x

return 2 * normal_probability_above(x, mu, sigma)

else:

# if x is less than the mean, the tail is what's less than x

return 2 * normal_probability_below(x, mu, sigma)

If we were to see 530 heads, we would compute:

two_sided_p_value(529.5, mu_0, sigma_0) # 0.062

One way to convince yourself that this is a sensible estimate is with a simulation:

extreme_value_count = 0

for _ in range(100000):

num_heads = sum(1 if random.random() < 0.5 else 0 # count # of heads

for _ in range(1000)) # in 1000 flips

if num_heads >= 530 or num_heads <= 470: # and count how often

extreme_value_count += 1 # the # is 'extreme'

print extreme_value_count / 100000 # 0.062

Since the p-value is greater than our 5% significance, we don’t reject the null. If we instead saw 532 heads, the p-value would be:

two_sided_p_value(531.5, mu_0, sigma_0) # 0.0463

which is smaller than the 5% significance, which means we would reject the null. It’s the exact same test as before. It’s just a different way of approaching the statistics.

Similarly, we would have:

upper_p_value = normal_probability_above lower_p_value = normal_probability_below

For our one-sided test, if we saw 525 heads we would compute:

upper_p_value(524.5, mu_0, sigma_0) # 0.061

which means we wouldn’t reject the null. If we saw 527 heads, the computation would be:

upper_p_value(526.5, mu_0, sigma_0) # 0.047

and we would reject the null.

## Confidence Intervals

We’ve been testing hypotheses about the value of the heads probability p, which is a parameter of the unknown “heads” distribution. When this is the case, a third approach is to construct a confidence interval around the observed value of the parameter.

For example, we can estimate the probability of the unfair coin by looking at the average value of the Bernoulli variables corresponding to each flip — 1 if heads, 0 if tails. If we observe 525 heads out of 1,000 flips, then we estimate p equals 0.525.

How confident can we be about this estimate? Well, if we knew the exact value of p, the central limit theorem (recall “The Central Limit Theorem”) tells us that the average of those Bernoulli variables should be approximately normal, with mean p and standard deviation:

math.sqrt(p * (1 - p) / 1000)

Here we don’t know p, so instead we use our estimate:

p_hat = 525 / 1000 mu = p_hat

sigma = math.sqrt(p_hat * (1 - p_hat) / 1000) # 0.0158

This is not entirely justified, but people seem to do it anyway. Using the normal approximation, we conclude that we are “95% confident” that the following interval contains the true parameter p:

normal_two_sided_bounds(0.95, mu, sigma) # [0.4940, 0.5560]

In particular, we do not conclude that the coin is unfair, since 0.5 falls within our confidence interval.

p_hat = 540 / 1000 mu = p_hat

sigma = math.sqrt(p_hat * (1 - p_hat) / 1000) # 0.0158

normal_two_sided_bounds(0.95, mu, sigma) # [0.5091, 0.5709]

Here, “fair coin” doesn’t lie in the confidence interval. (The “fair coin” hypothesis doesn’t pass a test that you’d expect it to pass 95% of the time if it were true.)

## P-hacking

A procedure that erroneously rejects the null hypothesis only 5% of the time will — by definition — 5% of the time erroneously reject the null hypothesis:

def run_experiment():

"""flip a fair coin 1000 times, True = heads, False = tails"""

return [random.random() < 0.5 for _ in range(1000)]

def reject_fairness(experiment):

"""using the 5% significance levels"""

num_heads = len([flip for flip in experiment if flip])

random.seed(0)

experiments = [run_experiment() for _ in range(1000)] num_rejections = len([experiment

for experiment in experiments

if reject_fairness(experiment)])

print num_rejections # 46

What this means is that if you’re setting out to find “significant” results, you usually can. Test enough hypotheses against your data set, and one of them will almost certainly appear significant. Remove the right outliers, and you can probably get your p value below 0.05. (We did something vaguely similar in “Correlation”; did you notice?)

This is sometimes called and is in some ways a consequence of the “inference from p-values framework.” A good article criticizing this approach is “The Earth Is Round.”

If you want to do good science, you should determine your hypotheses before looking at the data, you should clean your data without the hypotheses in mind, and you should keep in mind that p-values are not substitutes for common sense. (An alternative approach is “Bayesian Inference”.)

## Example: Running an A/B Test

Being a scientist, you decide to run an experiment by randomly showing site visitors one of the two advertisements and tracking how many people click on each one.

If 990 out of 1,000 A-viewers click their ad while only 10 out of 1,000 B-viewers click their ad, you can be pretty confident that A is the better ad. But what if the differences are not so stark? Here’s where you’d use statistical inference.

Let’s say that people see ad A, and that of them click it. We can think of each ad view as a Bernoulli trial where is the probability that someone clicks ad A. Then (if is large, which it is here) we know that is approximately a normal random variable with mean and standard deviation .

Similarly, is approximately a normal random variable with mean and standard deviation :

def estimated_parameters(N, n): p = n / N

sigma = math.sqrt(p * (1 - p) / N)

return p, sigma

If we assume those two normals are independent (which seems reasonable, since the individual Bernoulli trials ought to be), then their difference should also be normal with mean and standard deviation .

This means we can test the null hypothesis that and are the same (that is, that is zero), using the statistic:

def a_b_test_statistic(N_A, n_A, N_B, n_B):

p_A, sigma_A = estimated_parameters(N_A, n_A) p_B, sigma_B = estimated_parameters(N_B, n_B)

return (p_B - p_A) / math.sqrt(sigma_A ** 2 + sigma_B ** 2)

which should approximately be a standard normal.

For example, if “tastes great” gets 200 clicks out of 1,000 views and “less bias” gets 180 clicks out of 1,000 views, the statistic equals:

z = a_b_test_statistic(1000, 200, 1000, 180) # -1.14

The probability of seeing such a large difference if the means were actually equal would be:

two_sided_p_value(z) # 0.254

which is large enough that you can’t conclude there’s much of a difference. On the other hand, if “less bias” only got 150 clicks, we’d have:

z = a_b_test_statistic(1000, 200, 1000, 150) # -2.94

two_sided_p_value(z) # 0.003

which means there’s only a 0.003 probability you’d see such a large difference if the ads were equally effective.

## Bayesian Inference

The procedures we’ve looked at have involved making probability statements about our tests: “there’s only a 3% chance you’d observe such an extreme statistic if our null hypothesis were true.”

An alternative approach to inference involves treating the unknown parameters themselves as random variables. The analyst (that’s you) starts with a prior distribution for the parameters and then uses the observed data and Bayes’s Theorem to get an updated posterior distribution for the parameters. Rather than making probability judgments about the tests, you make probability judgments about the parameters themselves.

For example, when the unknown parameter is a probability (as in our coin-flipping example), we often use a prior from the Beta distribution, which puts all its probability between 0 and 1:

def B(alpha, beta):

"""a normalizing constant so that the total probability is 1"""

return math.gamma(alpha) * math.gamma(beta) / math.gamma(alpha + beta)

def beta_pdf(x, alpha, beta):

if x < 0 or x > 1: # no weight outside of [0, 1]

return 0

return x ** (alpha - 1) * (1 - x) ** (beta - 1) / B(alpha, beta)

Generally speaking, this distribution centers its weight at:

alpha / (alpha + beta)

and the larger alpha and beta are, the “tighter” the distribution is.

For example, if alpha and beta are both 1, it’s just the uniform distribution (centered at 0.5, very dispersed). If alpha is much larger than beta, most of the weight is near 1. And if alpha is much smaller than beta, most of the weight is near zero. Figure 7-1 shows several different Beta distributions.

So let’s say we assume a prior distribution on p. Maybe we don’t want to take a stand on whether the coin is fair, and we choose alpha and beta to both equal 1. Or maybe we have a strong belief that it lands heads 55% of the time, and we choose alpha equals 55, beta equals 45.

Then we flip our coin a bunch of times and see h heads and t tails. Bayes’s Theorem (and some mathematics that’s too tedious for us to go through here) tells us that the posterior distribution for p is again a Beta distribution but with parameters alpha + h and beta + t.

Figure 7-1. Example Beta distributions

Let’s say you flip the coin 10 times and see only 3 heads.

If you started with the uniform prior (in some sense refusing to take a stand about the coin’s fairness), your posterior distribution would be a Beta(4, 8), centered around 0.33. Since you considered all probabilities equally likely, your best guess is something pretty close to the observed probability.

If you started with a Beta(20, 20) (expressing the belief that the coin was roughly fair), your posterior distribution would be a Beta(23, 27), centered around 0.46, indicating a revised belief that maybe the coin is slightly biased toward tails.

And if you started with a Beta(30, 10) (expressing a belief that the coin was biased to flip 75% heads), your posterior distribution would be a Beta(33, 17), centered around 0.66. In that case you’d still believe in a heads bias, but less strongly than you did initially. These three different posteriors are plotted in Figure 7-2.

Figure 7-2. Posteriors arising from different priors

If you flipped the coin more and more times, the prior would matter less and less until eventually you’d have (nearly) the same posterior distribution no matter which prior you started with.

For example, no matter how biased you initially thought the coin was, it would be hard to maintain that belief after seeing 1,000 heads out of 2,000 flips (unless you are a lunatic who picks something like a Beta(1000000,1) prior).

What’s interesting is that this allows us to make probability statements about hypotheses: “Based on the prior and the observed data, there is only a 5% likelihood the coin’s heads probability is between 49% and 51%.” This is philosophically very different from a statement like “if the coin were fair we would expect to observe data so extreme only 5% of the time.”

Using Bayesian inference to test hypotheses is considered somewhat controversial — in part because its mathematics can get somewhat complicated, and in part because of the subjective nature of choosing a prior. We won’t use it any further in this book, but it’s good to know about.